Figure 6 | Laboratory Investigation

Figure 6

From: DA-1229, a dipeptidyl peptidase IV inhibitor, protects against renal injury by preventing podocyte damage in an animal model of progressive renal injury

Figure 6

Effects of DA-1229 on DPPIV activity in the plasma and kidneys and urinary excretion of nephrin in the adriamycin-induced nephrotoxicity model. (a) DPPIV activity in the plasma and kidneys. (b) Effects of preventive and therapeutic DA-1229 on plasma DPPIV activity. (c) Effects of DA-1229 on renal DPPIV activity. (d) Concentrations of active GLP-1. (e, f) Urinary excretion of nephrin in the model of adriamycin-induced nephrotoxicity. Values are expressed as means±s.e.m. *P<0.05 vs normal mice group; #P<0.05, ###P<0.001 vs adriamycin group.

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