Figure 1 | Laboratory Investigation

Figure 1

From: Longitudinal, in vivo assessment of invasive pulmonary aspergillosis in mice by computed tomography and magnetic resonance imaging

Figure 1

CT of mouse lungs infected with Aspergillus fumigatus. (a) Coronal CT images of representative mouse lungs after intranasal instillation with saline (control, top row) or A. fumigatus FGSC A1258 (infection, bottom row). A manually defined ROI is shown by the dashed line. (b) Graph representing the cumulative image score derived from the CT images of mice instilled with saline or A. fumigatus spores (ASFU 1731 or FGSC A1258 strain). (c–e) Graphs representing the signal intensity, lung tissue volume and total lung volume quantified from the CT lung images. Error bars represent s.d. of multiple mice (saline: n=5, ASFU 1731: n=7–10, FGSC A1258: n=7–8). *P<0.05; ***P<0.001; ****P<0.0001.

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