Figure 5
From: Musashi-2 promotes migration and invasion in bladder cancer via activation of the JAK2/STAT3 pathway
Msi2 activates JAK2/STAT3 signaling pathway. (a, b) Western blotting analysis indicating an apparent overlap between Msi2 expression and phosphorylation of JAK2 and STAT3, and the expression of WASF3, a key downstream effector of JAK2/STAT3 pathway. (c) Real-time PCR analysis shows WASF3 expression in Msi2-transduced and Msi2-silenced J82 and EJ cells. Bar graphs show the statistical analysis of three independent experiments (*P<0.05).
