Figure 2 | Laboratory Investigation

Figure 2

From: Mixed cell therapy of bone marrow-derived mesenchymal stem cells and articular cartilage chondrocytes ameliorates osteoarthritis development

Figure 2

Enhanced in vitro chondrogenic differentiation in the co-culture of human BMSCs+ACCs. BMSCs only, ACCs only, or BMSCs+ACCs (1:1) were differentiated in chondrogenic induction medium for 3 weeks and analyzed by (a) gross morphology and safranin-O staining analysis of chondrogenic differentiated BMSCs, ACCs, and ACCs+BMSCs pellets; (b) chondrocyte pellet size; (c) pellet wet weight; (d) total sGAG/DNA content; and (e) MTT cell proliferation assay. *P<0.05, results are representative of studies performed in three different patient samples with two technical replicates. Data are reported as means±s.d.; *P<0.05.

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