Figure 3
From: APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury

Effect of APX-115 on renal function. (a) Twenty-four hour urine albumin excretion after 12 weeks of treatment. (b) Plasma creatinine level. (c) Semi-quantitative scoring of the kidney as described in the ‘Materials and Methods’. *P<0.05, **P<0.01, ***P<0.001 vs db/m groups, #P<0.05, ##P<0.01, ###P<0.001 vs db/db control.