Table 2 Tissue mass change in experimental animals

From: APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury

Parameters

week

db/m

db/m +APX-115

db/db

db/db +GKT

db/db +APX-115

Kidney (g)

12

0.34±0.04

0.35±0.01

0.45±0.02*

0.43±0.04*

0.44±0.02*

Heart (g)

12

0.15±0.01

0.15±0.01

0.14±0.01

0.13±0.01

0.13±0.01

Fat (g)

12

0.92±0.09

0.93±0.05

2.91±0.11***

2.61±0.20***

2.32±0.22***

Liver (g)

12

1.48±0.05

1.45±0.06

3.19±0.27***

2.91±0.18**

3.13±0.22***

  1. *P<0.05, **P<0.01, ***P<0.001 vs db/m mice.
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