Figure 2 | Laboratory Investigation

Figure 2

From: Whole tumor section quantitative image analysis maximizes between-pathologists’ reproducibility for clinical immunohistochemistry-based biomarkers

Figure 2

Example cases of pathologists’ fields-of-view selection and potential variability for image analysis. Scored fields-of-view are noted per case (high-power images) with image analysis overlay indicating positive (red) and negative (green) cells and individual fields-of-view quantitative scores determined by the respective algorithm (% or X+). Fields-of-view are noted in relation to the overall tumor location (green rectangles, low-power image) and culminated quantitative case score. Ground truth for each case was determined by an independent consensus panel of three pathologists.

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