Table 1 NSG embryo injection data by CRISPR/Cas9 dose

From: Rapid generation of Col7a1−/− mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

Dose

Injected

Implanted

Pups

% Viability

Blistered

Non-blistered

% KO

Low

188

144

35

24%

12

23

34%

Med

303

231

39

16%

27

12

69%

High

505

348

79

22%

66

13

83%

High (B6)

215

130

36

27%

27

9

75%

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