Table 1 Angiogrine factors produced by the vascular niche
From: Bone marrow vascular niche and the control of tumor growth in hematological malignancies
Angiopoietin 2 (Ang-2) |
Bone morphogenetic protein-2 and -4 (BMP-2 and BMP-4, respectively) |
Brain-derived nerve growth factor (BDNGF) |
Endothelin-1 (ET-1) |
Fibroblast growth factor-2 (FGF-2) |
Granulocyte-colony stimulating factor (G-CSF) |
Granulocyte macrophage-colony stimulating factor (GM-CSF) |
Insulin-like growth factor (IGF) |
Interleukin-6 and -8 (IL-6 and IL-8, respectively) |
Laminin α4 |
Monocyte chemotactic protein-1 (MCP-1) |
Nitric oxide (NO) |
Pigmented-derived epithelial factor (PEDF) |
Placental growth factor (PlGF) |
Platelet-derived growth factor B (PDGFB) |
Stromal cell-derived factor-1 (SDF-1) |
Transforming growth factor beta (TGF-β) |
Vascular endothelial growth factor A (VEGF-A) |