Table 1 Sensitivity, specificity and both positive and negative predictive values of the PCA-based classification approach for B-CLPD according to the expression of CD22, CD23, CD20, CD103, CD25, CD11c, CD43, CD79b, FMC7, CD24, CD34, CD5, sIgM, CD27, Cybcl2, CD10 and CD38 on neoplastic B-cells
Diagnostic Subgroups | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
---|---|---|---|---|
Total B-CLL | 91% | 100% | 100% | 88% |
Typical B-CLL | 99% | 100% | 100% | 99% |
Atypical B-CLL | 55% | 100% | 100% | 89% |
MCL | 97% | 96% | 77% | 99% |
FL | 92% | 98% | 85% | 99% |
Other | 59% | 94% | 53% | 96% |
Total | 89% | 96% | 89% | 96% |