Figure 4

Fusion proteins PinX1C–G₄S–9R–G₄S–mBAFF and PinX1C-9R-mBAFF selectively induce apoptosis of BAFF receptor-expressing cells. Raji (a) and Jurkat (b) cells were treated in triplicate with 250-nM fusion proteins for 5 days, and apoptosis was then measured using flow cytometry after staining cells with annexin V-PI. Specific apoptosis in comparison with control cell death was calculated and presented as a percentage of control. The results are expressed as mean±s.e.