Table 4 Prognostic factors for the prediction of overall survival of the transplant patients (121 patients, 77 deaths) (multivariable Cox proportional hazard model)

From: Outcome of patients activating an unrelated donor search: the impact of transplant with reduced intensity conditioning in a large cohort of consecutive high-risk patients

Variables

HR (95% CI)

P-value

Conditioning regimen (A vs B)

0.95 (0.57–1.57)

0.833

Sex (F vs M)

0.87 (0.52–1.46)

0.604

Age (⩾50 vs <50 years)

1.46 (0.81–2.63)

0.211

Diagnosis (lymphoid vs myeloid malignancies)

0.88 (0.46–1.68)

0.689

Stem cell origin (BM vs PB)

1.14 (0.71–1.84)

0.583

Disease status (high-risk vs standard phase)

1.50 (0.86–2.62)

0.151

Time from donor search activation to transplant (⩾5 vs <5 months)

1.04 (0.64–1.69)

0.869

Engraftment (yes vs no)a

0.29 (0.13–0.64)

0.002

Acute GVHD (yes vs no)a

1.33 (0.81–2.20)

0.260

Chronic GVHD (yes vs no)a

0.47 (0.24–0.89)

0.020

  1. Abbreviations: BM, bone marrow; CI, confidence interval; F, female; GVHD, graft versus host disease; HR, hazard ratio; M, male; PB, peripheral blood.
  2. aTime-dependent covariate.
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