Figure 1 | Leukemia

Figure 1

From: Laboratory recommendations for scoring deep molecular responses following treatment for chronic myeloid leukemia

Figure 1

LoD of BCR-ABL1 detection. The graph shows the Poisson distribution with a mean of 3 BCR-ABL1 targets per well. The percentage of wells with 0–10 targets per well is indicated (20 000 computer-generated random datapoints; Minitab version 16, Coventry, UK) and shows that 95% of wells has at least one BCR-ABL1 target. As the LoD is defined as the lowest concentration of target that can be detected with 95% confidence, the maximal theoretical LOD is 3 copies.

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