Table 2 Characteristics of bleeding and nonbleeding patients

From: Ristocetin-induced platelet aggregation for monitoring of bleeding tendency in CLL treated with ibrutinib

Characteristic

Bleeding

No bleeding

P-value

Total number (n=64)

39/64 (60.9%)

25/64 (39.1%)

NA

Median body weight, kg (range)

74 (48–108)

69.5 (44–114)

0.49

Male, %

64.1%

64%

0.99

Antiplatelet or anticoagulant Tx

13/39 (33.3%)

5/25 (20%)

0.25

Antiplatelet therapy

8/39 (20.5%)

4/25 (16%)

0.65

Oral AC/heparin

6/39 (15.4%)

1/25 (4%)

0.15

Median platelet count, G/l (range)

116.5 (38–303)

137 (51–328)

0.0012

Median hemoglobin, mg/dl (range)

12.6 (9.2–16.7)

12.1 (8.3–17.1)

0.16

Median WBC, G/l (range)

21.8 (4.3–347.8)

16.0 (2.2–397)

0.41

  1. Abbreviations: AC, anticoagulant; NA, not available; Tx, treatment; WBC, white blood cell count. Bold value indicates significant P-value.