Table 4 Multivariable Cox regression model for overall survival

From: High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study)

Characteristics

Hazard ratio

95% CI

P-value

Age (continuously)

1.05

0.97–1.13

0.2178

Serum LDH (normal vs elevated)

1.14

0.64–2.03

0.6511

Location (supratentorial vs infratentorial)

1.18

0.62–2.26

0.6140

KPS (<70 vs ⩾70)

1.29

0.71–2.33

0.4051

Treatment (R-MPL vs R-MP)

0.98

0.52–1.86

0.9520

  1. Abbreviations: CI, confidence interval; KPS, Karnofsky Performance Score; LDH, lactate dehydrogenase; R-MPL, rituximab/methotrexate/procarbazine/lomustine; R-MP, R-MPL without lomustine.
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