Figure 6
From: EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia
Effect of EphA3 activation on signaling and internalization. (a) Representative images of treated cells at 0 and 20 min. (b) Increase in internalization score upon IIIA4 or ephrinA5-Fc treatment after 20min incubation at 37 °C in LK63 cells. (c) Median internalization score upon IIIA4 and ephrinA5-Fc treatment at 0 or 20 min after incubation at 37 °C in LK63 cells. (d) Percentage of cells that are internalized or colocalized at time 0 or 20 min after IIIA4 or ephrinA5-Fc treatment. In each AMNIS experiment, 5000 cells were collected and the experiment was repeated two times.
