Figure 6

Analysis of PB composition of AE9a and AE9aNT mice at indicated time points post transplant. (a) Levels of B220⁺ cells within the GFP positive/Ly5.1⁻ cell population. (b) CD3⁺ cells within the GFP⁺ /Ly5.1⁻ cell population in PB over time (^nsNot significant, *P<0.05, **P<0.01, unpaired Student’s t-test). Mean values based on the number of animals. (c) Flow cytometric measurement of myeloid progenitor cells (lineage⁻/Sca-1⁻/c-kit⁺ [L⁻S⁻K⁺]), granulocyte/macrophage progenitors (GMP); (CD16/32⁺, CD34⁺), CMP (common myeloid progenitors; CD16/32⁻, CD34⁺) and megakaryocyte-erythrocyte progenitors (MEP); (CD16/32⁻, CD34⁻) in the GFP⁺ BM cell population of control (green) and AE9aNT (blue) transplanted mice after approximately 2 years post transplantation. Mean values based on the numbers of animals.