Figure 2
From: RNA editing signature during myeloid leukemia cell differentiation
PMA treatment in U-937 cells induces the expression of both ADAR1 and ADAR2. Total RNA extracted from triplicates of U-937 cells, treated with PMA (80 nM) for 48 or 96 h, underwent RNA-seq analysis. (a) RNA expression level of selected genes belonging to the inflammatory/differentiation pathways (triplicates). (b) ADAR1 and ADAR2 expression (FPKM, triplicates). (c) One representative of three western blots of ADAR1, ADAR2 and p21 in PMA-treated U-937 cells. *P<0.01; **P<0.001. FPKM, fragments per kilobase of exon per million fragments mapped.
