Figure 2 | Leukemia

Figure 2

From: Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups

Figure 2

Structural rearrangements in IgHVunmut and IgHVmut CLL. Circos plot depicting the frequency and locations of CNAs and translocations detected in 46 CLL genomes. The two outermost tracks represent CNAs: CN loss (red) and CN gain (green). Copy number data is displayed as the percentage of each IgHV subgroup affected. The centre plot shows translocations identified in the cohort. Red links indicate tier 1 events (gene:gene), green links indicate tier 2 events (gene:intergenic) and grey indicate tier 3 (intergenic:intergenic). The widths of the bands are indicative of the number of patients affected by the translocation.

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