Figure 5 | Leukemia

Figure 5

From: Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

Figure 5

GATA2 mutants differentially impact clonogenic expansion and hematopoietic differentiation. (a) Enumeration of absolute colony numbers. GATA2 WT (hatch) was used as a comparator for all analyses. (b–e) Colonies were typed by morphology and numbers were reported. (b) Granulocyte CFU (CFU-G), (c) colony formation for granulocyte–macrophage/granulocyte, erythrocyte, monocyte and megakaryocyte progenitors (CFU-GM/GEMM), (d) macrophage CFU (CFU-M) and (e) BFU-E. All results are plotted as mean±s.e.m. with n independent biological replicates. ns: not significant, *P<0.05 and **P<0.01.

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