Figure 6 | Leukemia

Figure 6

From: Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes

Figure 6

Summary of functional assays for GATA2 mutant allelic series in this study. GATA2 mutants are listed in descending order of DNA-binding affinity. Results of transactivation, co-IP, subcellular localization, structural changes and colony assays are summarized. DEL indicates partial or whole gene deletion and mutants with premature termination; Nc, nuclear; ND, not determined. #See Greif et al.24 *See Kazenwadel et al.34 ^See Cortes-Lavaud et al.47

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