Figure 3 | Leukemia

Figure 3

From: Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia

Figure 3

TKI treatment response of AML cells. (a) Representative flow cytometry plots and (b) bar graph showing the FLT3 surface expression in AML cells, harboring different FLT3 genotypes, with or without AC220 treatment (mean±s.d.). A mean fluorescence intensity (MFI) ratio increase of ⩾0.50 is highlighted by an arrow. (c) Viable cell counts of selected AML cells, normalized to untreated control, after 72 h of treatment with increasing concentrations of AC220 (n=3, mean±s.d.).

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