Figure 6 | Leukemia

Figure 6

From: Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia

Figure 6

TKI effect on FLT3 surface expression in patients. (a) Flow cytometry plots showing the FLT3 surface expression before (day 0) and after (indicated day) TKI treatment. A mean fluorescence intensity (MFI) ratio increase of ⩾0.50 is highlighted by an arrow. (b) Sorafenib treatment scheme with indication of the time point of relapse (R), sampling of bone marrow (BM) and peripheral blood (PB) for the assessment of treatment response. Arrows indicate dosage adjustments.

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