Figure 3

S1P activates Akt in HRS cells mediated by differential expression of S1P receptors. (a) Immunoblot of KMH2 cells following S1P stimulation and (b) following 1 h pre-treatment with increasing concentrations of Ozanimod or Siponimod.
S1P activates Akt in HRS cells mediated by differential expression of S1P receptors. (a) Immunoblot of KMH2 cells following S1P stimulation and (b) following 1 h pre-treatment with increasing concentrations of Ozanimod or Siponimod.