Table 1 Patients' baseline characteristics at the time of sampling

From: Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia

Parameter

Category

CLL (n=406)

Gender

% male/female

57/43

Age (years)

Median (range)

66 (19–94)

Time from diagnosis to sampling (months)

12

206

 

>12

200

Binet stage

A

315

 

B

52

 

C

15

 

Unknown

24

Rai stage

0

254

 

I–II

110

 

III–IV

17

 

Unknown

25

Copy number alterations

tri(12)

54/376 (14.3%)

 

del(13q)

163/376 (43.4%)

 

del(17p)

15/376 (4%)

 

del(11q)

37/376 (9.8%)

IGHV mutational status

Mutated

218/382 (57.1%)

Patients treated during follow-up

n (%)

211/406 (53%)

Follow-up from sampling (years)

Median (range)

4.3 (0.01–19.1)

  1. Abbreviations: Del, deletion; IGHV unmutated, 98% identity with germ line.