Figure 4 | Leukemia

Figure 4

From: RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia

Figure 4

Evolution of clonal and subclonal RAS pathway mutations between initial diagnosis and subsequent relapse in 13 BCP-ALL cases. Variant allele frequency of all RAS pathway mutations found at initial diagnosis and/or relapse(s) is shown for cases with RAS pathway mutations detected at either time point (13 of 19). Colors distinguish affected genes; symbols distinguish observed variants. Dx, initial diagnosis sample; R, relapse sample.

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