Figure 7
From: Label-free super-resolution imaging of adenoviruses by submerged microsphere optical nanoscopy

Numerical simulation of microsphere-based nano-imaging in a water environment. (a) The scalar electric-field distribution when a parallel light beam is incident onto the substrate with sub-diffraction-limit fine structures, which represents the standard configuration of the microscope under the transmission mode. (b) The scalar electric-field distribution without considering the top semi-sphere reflection effect. (c) The schematic diagram of the top semi-sphere reflection in the transmission mode. (d) The scalar electric-field distribution considering the top semi-sphere reflection effect or by reflective mode light illumination, where the ‘reflected’ light or the illuminated light through the microsphere is simulated as two-sphere coupling. (e) The scalar electric-field distribution under the reflection mode.