Figure 3

Confocal laser scanning microscopy images of HeLa cells incubated with GNR@SiO2(19 nm)@CaF2:Yb3+,Er3+ hybrid nanostructures (top row: a, bright field image; b, green channel image; c, red channel image and d, overlay imaging.) and CaF2:Yb3+,Er3+ NCs (bottom row: e, bright field image; f, green channel image; g, red channel image and h, overlay imaging).