Table 1 LSS endoscopic imaging performance comparison vs. recently commercialized optical technologies to provide biopsy guidance for detecting dysplasia in BE

From: Multispectral light scattering endoscopic imaging of esophageal precancer

Technique

Method

Sites

Patients

Sensitivity %

Specificity %

Operator Independent

Entire Surface

Ref

AFI

B

74

63

56/75**

78/76**

 

√

41

AFI+HRE

B

74

63

64/84**

83/85**

  

41

OCT

B

177

55

83

75

 

√

46

 

B

314

33

68

82

  

47

CLE

B/P

4008*

709

70/89

91/75

  

51

 

B/P

3493*

346

58/79

90/90

  

52

LSS

B/P

411

57

88/96

91/97

√

√

This study

  1. B—per-biopsy evaluation; P—per-patient evaluation; AFI—autofluorescence imaging; AFI+HRE− autofluorescence imaging combined with high resolution endoscopy; OCT—optical coherence tomography; CLE—confocal laser endomicroscopy; LSS—light scattering spectroscopy; *meta-analysis; **non-experts/experts.
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