Figure 1
From: IL-21 comes of age as a regulator of effector T cells in the gut

IL-6-mediated IL-21 autocrine expression promotes Th17 cell differentiation and blocks inducible Treg (iTreg) induction. IFN-γ, interferon-γ; IL, interleukin; TGF-β, transforming growth factor-β; Th, T helper cell.