Figure 3
From: Advances in mast cell biology: new understanding of heterogeneity and function
Mechanisms of mast cell responses to pathogens. Mast cells secrete stored mediators and newly synthesized protein and lipid mediators in response to fungal, bacterial, viral, and helminth pathogens. Opsonized pathogens are recognized by Fc receptors and RNA and protein products of pathogens activate the toll-like receptors and dectin-1 pattern recognition receptors. Mast cells also respond to complement activation products.
