Table 1b MEP1A minor allele frequencies in IBD vs. controls

From: MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease

ID a

UC

CD

Controls

P- value UC b

P- value CD b

732

0.433

0.362

0.349

0.0012

0.53

1414

0.402

0.353

0.338

0.03

0.59

1435

0.039

0.024

0.029

0.27

0.58

1620

0.015

0.036

0.033

0.04

0.8

1674

0.335

0.390

0.422

0.002

0.27

1825

0.258

0.264

0.25

0.75

0.58

1909

0.256

0.258

0.254

0.97

0.9

2326

0.349

0.372

0.396

0.1

0.42

2417c

0.25

0.31

0.392

2 × 10 −7

0.003

  1. CD, Crohn's disease; IBD, inflammatory bowel disease; UC, ulcerative colitis.
  2. aPolymorphism ID according to position on mRNA GenBank acc. NM_005588 17 Nov 2006 (A of the AUG initiation codon=10).
  3. bSignificant associations are highlighted in bold.
  4. cNucleotide position with reference to mRNA GenBank acc. NM_005588, which lacks the 12-nt insert.
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