Table 2 Genetic models for rs1059276 in UC

From: MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease

Model a

OR (95% CI)

P- value b

Allelic (A vs. C)

1.94 (1.51–2.49)

1.80 × 10−7

Recessive (AA vs. CC+CA)

2.46 (1.76–3.45)

1.34 × 10−7

Dominant (CC vs. AA+CA)

0.49 (0.29–0.85)

9.51 × 10−3

  1. CI, confidence interval; OR, odds ratio; UC, ulcerative colitis.
  2. aRisk allele=A.
  3. bPearson's goodness-of-fit χ2 (degree of freedom)=1.
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