Figure 7 | Mucosal Immunology

Figure 7

From: Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection

Figure 7

Local microbial translocation and immune activation in the colon results in systemic microbial translocation and immune activation in uninfected pigtail macaques. (a) The amount of lipopolysaccharide (LPS) measured in the colon significantly correlates with LPS in the mesenteric lymph node (LN). (b) The amount of MxA in the colon significantly correlates with the amount of MxA in the mesenteric LN. (c) LPS in the mesenteric LN significantly correlates with LPS in the axillary LN. (d) MxA in the mesenteric LN significantly correlates with MxA in the axillary LN. (e) LPS in the colon is associated with soluble CD14 (sCD14) in plasma. (f) MxA in the colon significantly correlates with sCD14 in plasma. Correlations determined by Spearman's rank correlation. Lines indicate linear regression.

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