Table 1 Levels of OVA-specific Ig in milk

From: Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development

 

OVA-specific Ig Concentration in milk (μg ml−1)

 

Unexposed non-sensitized mothers

OVA-exposed non-sensitized mothers

Unexposed sensitized mothers

OVA-exposed sensitized mothers

IgA

<0.5

<0.5

<0.5

23±3

IgG2a

<0.5

<0.5

<0.5

5.2±2

IgG1

<0.5

1.0±0.3

6.7±1.8

118±23

  1. Abbreviations: Ig, immunoglobulin; OVA, ovalbumin.
  2. Breast milk from unexposed or OVA-exposed non-sensitized or sensitized mothers was collected, pooled, and analyzed for the presence of OVA-specific IgA, IgG2a, and IgG1 by ELISA. Data show the mean±s.e.m. of six experiments.
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