Figure 2 | Mucosal Immunology

Figure 2

From: Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia

Figure 2

Sustained expression of TL1A leads to goblet cell and Paneth cell hyperplasia in the small intestine. Representative (n=10) photomicrographs (original magnification × 100) of sections from the colon (a) and ileum (b) of a 24-week-old CD11c-TL1A transgenic (tg) or wild-type (wt) mouse. (c) High-magnification ( × 400) photomicrographs of granule-rich Paneth cells from the ileum of a CD11c-TL1A tg or wt mouse. Paraffin sections stained with hematoxylin and eosin (H&E). The numbers of goblet cells/villus and Paneth cells/crypt were determined by examining 60 individual villi and crypts from 6 CD11c-TL1A tg or wt mice.

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