Figure 7
From: Protective role of Toll-like receptor 4 in experimental gonococcal infection of female mice
PMNs from BALB/c-Lpsd mice are defective for killing N. gonorrhoeae. Gonococci were opsonized with 10% serum from BALB/c mice and then incubated with PMNs from normal and BALB/c-Lpsd mice. The number of gonococci recovered after 0, 45, and 90 min incubation is expressed as the percentage of bacteria recovered from PMNs incubated with bacteria that were pre-incubated in HI serum. Absolute values are provided in parentheses above the bars. These data are representative of two independent experiments, in which reduced recovery of N. gonorrhoeae occurred after 90 min incubation with BALB/c PMNs only (59.6 and 52.9% for each experiment). HI, heat inactivated; PMN, polymorphonuclear cell.
