Figure 5
From: Altered distribution of mucosal NK cells during HIV infection
IEL NK cells are more abundant than LP NK cells in both healthy and HIV-infected populations. (a) The total frequency of IEL and LP NK cells was counted per mm2 of colon tissue in healthy individuals, demonstrating that IEL NK cells are more abundant in the gut mucosa than LP NK cells **P<0.01. (b) Similarly, IEL NK cells exceeded the frequency of LP NK cells in the colon tissue of HIV-infected individuals **P<0.01. (c) Furthermore, the relationship between IEL and LP NK cells was explored, demonstrating no visible correlation in cell frequencies in healthy individuals, (d) but a significant correlation in HIV+ patients. HIV, human immunodeficiency virus; IEL, intraepithelial lymphocyte; LP, lamina propria; NK, natural killer.
