Figure 1
Spontaneous bacterial colonization in C57BL/6N Scnn1b-transgenic (Scnn1b-Tg+) mice. (a) Time-course analysis of total colony-forming units (CFUs) in bronchoalveolar lavage samples from Scnn1b-Tg+ mice (▪) and wild-type (WT) littermates (□). (Log10+1)-transformed data; n=number of mice/group; Student's t test **P<0.005, *P<0.05 vs. WT littermates. (b) Individual CFUs and bacterial species isolated from C57BL/6N Scnn1b-Tg+ mice. Each tick on the x axis represents an individual mouse. (c) Bacteria isolated from tongue, esophagus, and trachea, tissue homogenates of postnatal day (PND) 5 C57BL/6N Scnn1b-Tg+ mice and WT littermates. (Log10+1)-transformed data. Each tick on the x axis represents an individual mouse. CFUs in confluent plates could not be enumerated and were arbitrarily set at 2 × 107 CFU/tissue.
