Figure 7
Highly reactive secondary airway luminal T-cell responses to pulmonary Mycobacterium tuberculosis (M.tb) challenge in parenteral Bacillus Calmette–Guérin (BCG)-immunized/CF (culture filtrate)–treated hosts. (a) Experimental schema. (b, c) The absolute numbers and representative dot plots of antigen-specific T cells in the bronchoalveolar lavage (BAL; b) and lung interstitium (c) analyzed at various time points post-M.tb challenge in the mice immunized with BCG and not treated with CF (BCG) or immunized with BCG and treated with CF (BCG/CF). Data are expressed as mean values±s.e.m. of 4–5 mice per group, representative of two independent experiments. IFN, interferon; SAC, sacrifice.
