Figure 3
From: The role of neutrophils during intestinal inflammation
Biosynthetic pathways of pro- and anti-inflammatory mediators derived from polyunsaturated fatty acids involving 5-lipoxygenase (LO) from neutrophils. FLAP, 5-lipoxygenase-activating protein; H(P)-DHA, hydroxyperoxy docosahexanoic acid; H(P)-EPE, hydroxyperoxy eicosapentanoic acid; H(P)-ETE, hydroxyperoxy eicosatetraenoic acid; LTA4, leukotriene A4; PMN, polymorphonuclear leukocytes. (Adapted from Wang and DuBois,156 Tjonahen et al.,178 Serhan and Petasis,179 and Weylandt et al.180)
