Figure 6
Increased expression of tolerance-associated functions at later time points of conventionalization. Jejunum, ileum, and colon gene expression levels of regulatory cytokines were analyzed in germfree and conventionalized mice at indicated days post conventionalization. Values are depicted as box and whisker diagram (top-to-bottom; maximum value, upper quartile, median, lower quartile, and minimal value, respectively). Any data not included between the whiskers is plotted as an outlier with a dot. Significant differences between time-points are indicated by distinctive characters above the measurement groups (P<0.05), (n=6–11/day).
