Figure 4 | Mucosal Immunology

Figure 4

From: Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection

Figure 4

CD103+ dendritic cells (DCs) are lost after SIV infection, and associated with the frequency of IL-17- and IL-22-producing lymphocytes. (a, b) The frequency of live, lineage-, HLA-DR+ CD103+ dendritic cells (DCs) in the colon (a) or mesenteric lymph nodes (MLNs) (b). (c–e) The frequency of CD103+ DCs is compared with the frequency of IL-17-producing CD4+ T cells (c), CD8+ T cells (d), or CD3-CD8+ lymphocytes (e). (f–h) The frequency of CD103+ DCs is compared with the frequency of IL-22-producing CD4+ T cells (f), CD8+ T cells (g), or CD3-CD8+ lymphocytes (h). Closed circles, SIV− colon; closed triangles, SIV+ colon; open circles, SIV− MLNs; open triangles, SIV+ MLNs. Horizontal bars represent median and diagonal lines represent linear regression.

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