Figure 1 | Mucosal Immunology

Figure 1

From: Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice

Figure 1

Increase of total CD8 or CD4 T cells in cervix-vagina (CV) upon intravaginal (IVAG) CpG or PIC. Groups of C57BL/6 mice were IVAG instilled with phosphate-buffered saline (PBS), CpG, or PIC, and 3 days later cells recovered from single or pools of two CV were stained with CD8–APC antibodies and CD4–FITC antibodies, and analyzed by flow cytometry. A representative result for each group of mice is shown in (a). Percentage of total CD8 T cells (b) and total CD4 T cells (c) within the recovered CV cells are shown for each IVAG treatment. The horizontal bars represent the mean percentages. Significant differences are indicated by * for P<0.05 and *** for P<0.001.

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