Figure 4
From: Intestinal bacteria induce TSLP to promote mutualistic T-cell responses
Thymic stromal lymphopoietin (TSLP)-deficient mice exhibit a hyperplasia of colonic lymphoid follicles (LFs). (a) Histological sections from the colon of naive specific pathogen-free (SPF) C57BL/6 and TSLP receptor (TSLPR)−/− mice. Quantification of the (b) number of immature and mature LFs and (c) size of mature LFs in the same mice. (d) Representative microscopic picture of a mature LF from naive SPF C57BL/6 and TSLPR−/− mice. Data are from one representative experiment of two seperate experiments (n=3 per group). DAPI, 4,6-diamidino-2-phenylindole; IgA, immunoglobulin A. *P<0.05, **P<0.01, ***P<0.001.
