Figure 8
Interleukin (IL)-4Rα expressing lung-resident CD4+ T cells enhance protection to Nippostrongylus brasiliensis (NB) infection. (a) CD4+ T cells were isolated from the lungs of FTY720-treated N. brasiliensis–infected IL-4Rα-/lox or LckcreIL-4Rα-/lox mice and intranasally transferred into FTY720-treated naive BALB/c mice. (b) Naive mice were then infected with 500 L3 N. brasiliensis larvae, and worm burdens were quantified at 5 days post infection (PI). Data are representative of two individual experiments. N=4–6 mice per group. **P<0.01.
