Figure 5
D-series resolvins RvD1 and aspirin-triggered RvD1 (AT-RvD1) increase high molecular weight glycoconjugate secretion in conjunctival goblet cells. Increase in high molecular weight glycoconjugate secretion in (a and b) human and (c and d) rat conjunctival goblet cells. Concentration- and time-dependence of RvD1 (open circles) or AT-RvD1 (closed circles) stimulation of high molecular weight glycoconjugate secretion. Panels a and c represent 2-h stimulation with increasing concentrations of RvD1 and AT-RvD1. Panels c and d show 10−8 M resolvin stimulation for 0–4 h. Mean of three experiments for a–d. *P<0.05 (vehicle plus resolvin).
