Figure 4

Invariant natural killer T (iNKT) cells in the fetal small intestine have a differentiated phenotype. (a) CD4-iNKT cells in the fetus are exclusively CD161+. (b) Transitional stages of memory are present in the fetal spleen and mesenteric lymph node (MLN) iNKT population (upper panel). Fetal non-iNKT cells (CD1d-tet−Vα24+), lower panel. Representative fluorescence-activated cell sorting (FACS) plots are shown, n≥4.