Figure 7
From: Interleukin-4 and interferon-γ orchestrate an epithelial polarization in the airways
Interleukin-24 (IL-24) protein secretion in vitro and in vivo. (a) A signal for IL-24 secretion in vitro was detected by western blot analysis after 6 and 24 h of stimulation with IL-4 but not for interferon-γ (IFN-γ) or IL-4/IFN-γ cultivation of normal human bronchial epithelial cells (NHBEs). There was no detectable signal in medium controls. (b) Significantly upregulated secretion of IL-24 of patients in season (n=13) in comparison with healthy controls (n=14) was detected. An increased secretion of IL-24 could be detected for both patient groups compared with healthy controls.
