Figure 1
dM become more permissive to HIV-1 infection in cytokine-free culture. (a) Freshly purified dM were challenged with HIV-1/VSV-G at day 0, 3, and 7 of culture. HIV-1 replication was monitored by measuring luciferase activity (n=7). (b) dM were challenged with HIV-1BaL immediately after isolation (day 0) or after 7 days of cytokine-free culture. Viral production was followed by quantifying p24 Ag in the supernatant. p24 Ag production on day 21 post infection (n=7). Mean±s.e.m. of n independent donors. dM, decidual macrophages.
